G.M. de Boer will defend her PhD dissertation on Thursday, 30 November 2023, entitled: ’Wheezy Lungs in the Sneezy Seasons of Life: Asthma risk factors, immunomodulation and inflammatory dynamics‘.
- Promotor
- Co-promotor
- Co-promotor
- Date
- Thursday 30 Nov 2023, 13:00 - 14:30
- Type
- PhD defence
- Space
- Senate Hall
- Building
- Erasmus Building
- Location
- Campus Woudestein
Below is a brief summary about the dissertation:
Standard medical interventions, such as lifestyle interventions, inhaled medication and antihistamines, are not sufficient in approximately 5% of asthma patients; their asthma is defined as ‘severe asthma'.
Treatment options in those patients also consist of suppression of specific immunological pathways aimed at type 2 inflammation by monoclonal antibodies or “biologicals”. Despite the availability of these treatment options, some patients will still not reach adequate asthma control.
This is currently an unmet need that might result in overtreatment. In the past years, treatment of asthma has developed towards a more personalized approach taking the T2 status into account. This thesis comprises studies on risk factors for the development of asthma later in life and the effects of time and exacerbations on persistence and nature of asthma inflammation. Also, immunomodulation with bacterial lysates is being described, to prevent asthma exacerbations in children and adults, with uncontrolled asthma and recurrent exacerbations
- More information
The public defence will begin exactly at 13.00 hrs. The doors will be closed once the public defence starts, latecomers may be able to watch on the screen outside. There is no possibility of entrance during the first part of the ceremony. Due to the solemn nature of the ceremony, we recommend that you do not take children under the age of 6 to the first part of the ceremony.
A live stream link has been provided to the candidate.
