On Friday 28 May 2021, K.D. Bharwani will defend her PhD dissertation, entitled: ‘Complex Regional Pain Syndrome: the search for inflammatory biomarkers’.
- Promotor
- Co-promotor
- Date
- Friday 28 May 2021, 13:00 - 14:30
- Type
- PhD defence
- Space
- Senate Hall
- Building
- Erasmus Building
- Location
- Campus Woudestein
The aim of this thesis was to highlight and explore the need for inflammatory biomarkers in CRPS. To this end, this thesis was divided into 3 parts. Part 1 highlights the need for objective diagnostic and therapeutic biomarkers in CRPS, as this syndrome is currently diagnosed using only (relatively subjective) clinical criteria which often lead to a diagnostic and therapeutic delay. Part 2 explores the use of the T-cell specific soluble interleukin-2 receptor (sIL-2R) and macrophage-specific sCD163 in the diagnosis of CRPS and explores application of these biomarkers in the management of this syndrome. Part 3 addresses existing skepticism on the diagnosis CRPS. A systematic search is conducted looking for articles that deny the existence of this syndrome. Subsequently, the arguments that are presented in these articles are summarized and then refuted using the available empirical literature on CRPS. Ultimately, the goal of this thesis is to emphasize the importance of biomarker research in CRPS by exploring the role of inflammatory biomarkers in CRPS, thereby introducing more objectivity to the clinical diagnostic process and reducing subjectivity, and skepticism, surrounding the diagnosis CRPS.
Due to corona, the PhD defences do not take place publicly in the usual way in the Senate Hall or in the Professor Andries Querido Room. The candidates will defend their dissertation either in a small group or online.
