On 16 December 2021, M.A. Wefers Bettink will defend his PhD dissertation, entitled: ‘Mind the Mitochondria!’.
- Promotor
- Co-promotor
- Date
- Thursday 16 Dec 2021, 15:30 - 17:00
- Type
- PhD defence
- Space
- Senate Hall
- Building
- Erasmus Building
- Location
- Campus Woudestein
In the work we presented in this thesis we have shown robustness and sensitivity of the COMET monitoring technique in our pre-clinical work. The main goal, measuring mitochondrial dysfunction in sepsis, was partly achieved in our ICU study, we failed to reach sufficient participants to analyze the data. We were able to measure cellular oxygenation in patients under anesthesia and started to show the additional value of the COMET monitor as a monitor of cellular oxygenation during anesthesia. The electron transport chain and its production of adenosine triphosphate (ATP) is the best-known function of mitochondria. However, the role of mitochondria in homeostasis of the cell is not limited to the production of ATP.
The public defence will take place at the Senate Hall, 1st floor Erasmus Building, location campus Woudestein. The ceremony will begin exactly at 15.30 PM. In light of the solemn nature of the ceremony, we recommend that you do not take children under the age of 6 to the first part of the ceremony.
