PhD defence N. (Noreen) Mumtaz

Zika Virus Infection: In vitro models of disease pathogenesis

N. Mumtaz will defend her PhD dissertation on Friday 13 January 2023, entitled: ’Zika Virus Infection: In vitro models of disease pathogenesis‘.

Promotor
Prof. dr. M.P.G. Koopmans
Co-promotor
Dr. B.H.G. Rockx
Co-promotor
Dr. B.C.J. van der Eerden
Date
Friday 13 Jan 2023, 13:00 - 14:30
Type
PhD defence
Space
Senate Hall
Building
Erasmus Building
Location
Campus Woudestein
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Summary:

Historically, the emergence and re-emergence of arthropod-borne viruses have caused significant mortality and morbidity worldwide. Zika virus (ZIKV) is a mosquito-borne flavivirus responsible for human diseases causing diverse symptoms. Most ZIKV infections are asymptomatic or cause mild influenza-like symptoms including fever, rash, and
arthralgia/ arthritis, but severe complications in adults, including Guillain-Barre syndrome, and in neonates such as microcephaly are also reported. Despite growing knowledge and understanding about ZIKV pathogenesis, less is known about virus and host factors which otherwise will help to understand the biology of ZIKV infection. Pathogenesis studies are essential to decipher the interplay between host cells and virus and to identify disease
biomarkers and targets for therapeutics and preventive measures. In the current thesis, we have developed and characterized various in vitro models based on human cell types to study ZIKV pathogenesis.

More information

The public defence will begin exactly at 13.00 hrs. The doors will be closed once the public defence starts, latecomers may be able to watch on the screen outside. There is no possibility of entrance during the first part of the ceremony. Due to the solemn nature of the ceremony, we recommend that you do not take children under the age of 6 to the first part of the ceremony.

A live stream link has been provided to the candidate.

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