E. Ataei Ataabadi will defend his PhD dissertation on Wednesday 14 June 2023, entitled: ’Modulating NO-cGMP Signalling in Ageing Models‘.
- Promotor
- Co-promotor
- Date
- Wednesday 14 Jun 2023, 13:00 - 14:30
- Type
- PhD defence
- Space
- Professor Andries Querido room
- Building
- Education Center
- Location
- Erasmus MC
Summary:
The results of the present thesis emphasize the importance of genomic instability in inducing ageing-related problems. DNA damage appears to play a central role in triggering cardiovascular diseases, which cause a huge burden on the healthcare system. Therefore, exploring the association between DNA damage and cardiovascular disease via ageing models is a useful approach to address the questions in that field. At this stage, genetic epidemiological research supports an association between DNA repair gene single nucleotide polymorphisms and telomere attrition with cardiovascular remodelling and risk. Moreover, some progeria syndromes based on DNA repair defects are featured by cardiovascular death. Thus, DNA damage in human cardiovascular disease might also play a predictive role
- More information
The public defence will begin exactly at 13.00 hrs. The doors will be closed once the public defence starts, latecomers can access the hall via the fourth floor. Due to the solemn nature of the ceremony, we recommend that you do not take children under the age of 6 to the first part of the ceremony.
A live stream link has been provided to the candidate.
