On Wednesday, 29 Juni 2022, E.M.J. Beelen will defend her PhD dissertation, entitled: ‘Postoperative Recurrence of Crohn’s Disease after Ileocolonic Resection’.
- Promotor
- Co-promotor
- Date
- Wednesday 29 Jun 2022, 13:00 - 14:30
- Type
- PhD defence
- Space
- Professor Andries Querido room
- Building
- Education Center
- Location
- Erasmus MC
Dissertation in short:
The postoperative management of Crohn's disease is challenging, as postoperative recurrence is common and re-resection rates are high. A knowledge gap exists regarding postoperative risk stratification and the optimal treatment strategy, limiting under- and over-treatment. The aim of this thesis is to enhance knowledge on the postoperative recurrence of Crohn's disease after intestinal resection, with regards to epidemiology, prediction and prevention. The first part of this thesis focuses on epidemiology of intestinal resections and re-resections throughout the past decades. In addition, the risk of cholecystectomy after ileal resection is assessed. The second part describes the postoperative disease course and prediction of postoperative recurrence, specifically the timing of ileocecal resection, isolated inflammation of the ileal blind loop and Paneth cell function. The third part of this thesis focuses on the prevention of postoperative recurrence, with regards to a management strategy incorporating risk stratification and type of postoperative prophylactic medication.
- More information
The public defence will begin exactly at 13.00 hrs. The doors will be closed once the public defence starts, latecomers can access the hall via the fourth floor. Due to the solemn nature of the ceremony, we recommend that you do not take children under the age of 6 to the first part of the ceremony.
A live stream link has been provided to the candidate.