On 10 November 2021, K. Nesteruk will defend her PhD dissertation, entitled: ‘Detection and Molecular Characterization of Gastrointestinal Cancers and Premalignant Lesions’.
- Promotor
- Co-promotor
- Date
- Wednesday 10 Nov 2021, 13:00 - 14:30
- Type
- PhD defence
- Space
- Professor Andries Querido room
- Building
- Education Center
- Location
- Erasmus MC
The current thesis combines basic and translational studies on gastrointestinal carcinogenesis. The first part focused on the detection and treatment of pancreatic cancer. We demonstrate that detection of pancreatic cancer with biomarkers in pancreatic juice may feasible in the future. A better understanding of the molecular mechanisms underlying tumor formation and treatment may serve as a starting point for the development of better treatments for this disease.
The second part investigated gene-regulators of gastrointestinal embryogenesis in esophageal cancer pathogenesis. We show that genes that determine positional identity during embryogenesis also play an important role in adult physiology, and that disruption in these genes can contribute to gastrointestinal pathologies.
The public defence will take place at the Prof. Andries Queridoroom, 3rd floor Education Center, Erasmus MC. The ceremony will begin exactly at 13.00 PM. In light of the solemn nature of the ceremony, we recommend that you do not take children under the age of 6 to the first part of the ceremony.
