PhD defence L.M.R. (Louella) Kasbergen

Understanding Arbovirus Serology in a Changing World: Antibody landscapes and antibody cross-reactivity

On Wednesday 3 December 2025, L.M.R. Kasbergen  will defend the doctoral thesis titled: Understanding Arbovirus Serology in a Changing World: Antibody landscapes and antibody cross-reactivity

Promotor
Prof.dr. M.P.G. Koopmans
Co-promotor
Dr. R.S. Sikkema
Date
Wednesday 3 Dec 2025, 10:30 - 12:00
Type
PhD defence
Space
Professor Andries Querido room
Building
Education Center
Location
Erasmus MC
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Below is a brief summary of the dissertation:

This PhD research explores how infections with arboviruses transmitted by vectors, such as mosquitoes, can be serologically detected and diagnosed. With the ongoing rapid and worldwide spread of arboviruses, (closely-related) arboviruses increasingly co-circulate. This complicates serological interpretation and differentiation due to antibody cross-reactivity. This thesis aims to elucidate our understanding of the complex arbovirus antibody (background) patterns in low to high-risk populations, and ultimately to differentiate past and recent infections with closely-related viruses. The thesis describes various applications of innovative multiplex approaches to study arbovirus antibodies and their complex interplay.

More information

The public defence will start exactly at 10.30 hrs. The doors will be closed once the public defence starts, latecomers cannot access the hall. Given the solemn nature of the meeting, we advise not to bring children under the age of 6 to the first part of the ceremony. 

 
A livestream link has been provided to candidate. 

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