PhD defence M. (Meedie) Ali

Gray Matter(s) in Multicolor: Intraoperative delineation and treatment of glioblastoma and its infiltrative edge

On Wednesday 4 Februari 2026,  M. Ali will defend the doctoral thesis titled: Gray Matter(s) in Multicolor: Intraoperative delineation and treatment of glioblastoma and its infiltrative edge

Promotor
Prof.dr. C.M.F. Dirven
Promotor
Prof.dr. C.W.G.M. Löwik
Co-promotor
Dr. L. Mezzanotte
Co-promotor
Dr. R.K. Balvers
Date
Wednesday 4 Feb 2026, 10:30 - 12:00
Type
PhD defence
Space
Professor Andries Querido room
Building
Education Center
Location
Erasmus MC
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Below is a brief summary of the dissertation:

In this dissertation, we have focused on novel intraoperative approaches that might assist or 
even enhance the (surgical) treatment paradigm for GBM patients. Two of the most prominent 
intraoperative approaches we studied included image-guided surgery and photodynamic 
therapy with the use of targeted probes. The overall aim of the thesis has been to evaluate these probes in (pre)clinical models and to develop these approaches for eventual clinical application. Although (pre)clinical drug development is a very long and arduous process, we believe that our work in this thesis has laid the foundation required to test one of these probes, FA-ICG, in an upcoming phase I trial for image-guided surgery of GBM.

More information

The public defence will start exactly at 10.30 hrs. The doors will be closed once the public defence starts, latecomers cannot access the hall. Given the solemn nature of the meeting, we advise not to bring children under the age of 6 to the first part of the ceremony. 

 
A livestream link has been provided to candidate. 

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