On 23 November 2021, P. Heukels will defend his PhD dissertation, entitled: ‘Adaptive Immunity in Interstitial Lung Diseases and Pulmonary Hypertension’., entitled: ‘Adaptive Immunity in Interstitial Lung Diseases and Pulmonary Hypertension’.
- Promotor
- Co-promotor
- Date
- Tuesday 23 Nov 2021, 10:30 - 12:00
- Type
- PhD defence
- Space
- Professor Andries Querido room
- Building
- Education Center
- Location
- Erasmus MC
The lungs are constantly exposed to inhaled agents that may induce an inflammatory response. The inflammatory response encompasses several stages, starting with the influx of activated inflammatory cells, and ending with tissue repair and restoration of tissue function. When the delicate balance between inflammation and resolution becomes dysregulated, ongoing inflammation can lead to tissue remodeling or fibrosis. In interstitial lung diseases and pulmonary hypertension, the big question is whether the observed changes in adaptive immunity are a critical trigger for disease onset and progression in susceptible patients or a consequence of established disease. The findings described in this thesis contribute to our knowledge on the immune-related pathogenesis of interstitial lung diseases and pulmonary hypertension. Combining the immunological mechanisms with disease behavior, response to therapy and patients’ perspectives will help to advance patient-tailored care.
The public defence will take place at the Prof. Andries Queridoroom, 3rd floor Education Center, Erasmus MC. The ceremony will begin exactly at 10.30 AM. In light of the solemn nature of the ceremony, we recommend that you do not take children under the age of 6 to the first part of the ceremony.
