On Tuesday 25 October 2022, S. Udomkarnjananun will defend his PhD dissertation, entitled: ‘Predicting Kidney Transplantation Outcomes and Exploring Novel Matrices for Therapeutic Drug Monitoring of Tacrolimus’.
- Promotor
- Co-promotor
- Date
- Tuesday 25 Oct 2022, 10:30 - 12:00
- Type
- PhD defence
- Space
- Professor Andries Querido room
- Building
- Education Center
- Location
- Erasmus MC
Dissertation in short:
The overarching aim of the research described in this thesis was the development of various models and algorithms to predict post-transplantation complications and outcomes,
as well as the response to immunosuppressive therapy, particularly tacrolimus. Although tacrolimus is the backbone of immunosuppression after kidney transplantation, treatment with
this drug is complicated by its many side effects and its high intra- and inter-individual pharmacokinetic variability. Therapeutic drug monitoring (TDM) is routinely performed to optimize
tacrolimus therapy, i.e. to increase its efficacy and to minimize tacrolimus’ side effects. However, although the use of TDM enables a more personalized approach to pharmacologic
immunosuppression, the current TDM strategy has important limitations.
- More information
The public defence will begin exactly at 10.30 hrs. The doors will be closed once the public defence starts, latecomers can access the hall via the fourth floor. Due to the solemn nature of the ceremony, we recommend that you do not take children under the age of 6 to the first part of the ceremony.
A live stream link has been provided to the candidate.
