PhD defence S.A.J. (Samuel) Fidder

Rejection, Desensitization, and Tissue Preservation in Male Urogenital Allotransplantation

On Thursday, 16 June 2022, S.A.J. Fidder will defend his PhD dissertation, entitled: ‘Rejection, Desensitization, and Tissue Preservation in Male Urogenital Allotransplantation’.

Promotor
Prof. dr. S.E.R. Hovius
Co-promotor
Dr. D. Vasilic
Co-promotor
Prof. G. Brandacher
Date
Thursday 16 Jun 2022, 15:30 - 17:00
Type
PhD defence
Space
Senate Hall
Building
Erasmus Building
Location
Campus Woudestein
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Dissertation in short:

To flourish as a human being one does not only require organs, but also a face that enables communication, hands that can cook food, and genitalia that are functional. In the field of reconstructive transplantation these needs are met through the replacement of such functional body parts that were previously lost with donor tissue from a different (deceased) person. Now 25 years after the first hand transplant, face- arm- and penis transplants have been performed across the world.

Many challenges remain for the field of reconstructive transplantation. Currently, relatively little is known about the unique rejection patterns of penis- and hand transplants. Additionally, transplants can only be preserved for short time periods and patients who went through pregnancy or received blood transfusions often cannot receive a transplant due to the immunological memory they developed. This thesis consists of studies that address these issues through experiments in rats and pigs. Additionally, the ethical considerations related to penis transplants are discussed and the extensive transplant of a penis, scrotum, and abdominal wall in a soldier who was wounded through an IED blast is described.

More information

The public defence will begin exactly at 15.30 hrs. The doors will be closed once the public defence starts, latecomers may be able to watch on the screen outside. There is no possibility of entrance during the first part of the ceremony. Due to the solemn nature of the ceremony, we recommend that you do not take children under the age of 6 to the first part of the ceremony.

A live stream link has been provided to the candidate.

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