On 17 September 2021, W.J. Goedegebuure will defend his PhD dissertation, entitled: ‘Small for Gestational Age: Adult metabolic and cardiovascular health and long-term safety of growth hormone treatment’.
- Promotor
- Co-promotor
- Date
- Friday 17 Sep 2021, 13:00 - 14:30
- Type
- PhD defence
- Space
- Senate Hall
- Building
- Erasmus Building
- Location
- Campus Woudestein
This thesis describes the concluding research that has been conducted in a large population of (young) adults who were born small for gestational age (SGA). Around 10% of children born SGA, do not experience catch-up growth, which leads to persistent short stature until adulthood. Growth hormone treatment and postponing puberty with gonadotropin-releasing hormone agonist (GnRHa) can lead to sufficient catch-up in height, which results in an adult height within the normal range. However, long-term effects of SGA birth, growth hormone and GnRHa treatment were unknown. We describe long-term effects of SGA birth and these treatments on metabolic and cardiovascular health, body composition, bone mineral density, kidney function, cognition and psychosocial functioning.
The PhD defences do not take place publicly in the usual way in the Senate Hall at campus Woudestein or in the Professor Andries Querido Room at the Erasmus MC. The candidates will defend their dissertation either in a small group or online.
