Stop and Start; how cells cope with DNA damage that interferes with transcription.
Dr ir. J. A. F. (Jurgen) Marteijn
Erasmus MC, Department of Molecular Genetics
DNA damage impedes transcription. This can result in severe cellular dysfunction and accelerated aging. Dr ir Jurgen Marteijn will use an innovative microscopic analysis method to study effects of DNA damage on transcription in living cells. Combined with advanced protein analysis, the scientists will study how cells cope with transcription-blocking DNA damage.