- Promotor
- Promotor
- Promotor
- Date
- Wednesday 31 May 2023, 13:00 - 14:30
- Type
- PhD defence
- Space
- Professor Andries Querido room
- Building
- Education Center
- Location
- Campus Woudestein
E.M. Pluijms will defend her PhD dissertation on Wednesday 31 May 2023, entitled: ’Electroconvulsive Therapy for Severe Depression‘.
Summary:
Major depressive disorder (major depression) is a common, sometimes life-threatening mental illness that often has a major impact on daily life. Therefore, an effective treatment is essential. One treatment option is electroconvulsive therapy (ECT). Although ECT is the most effective treatment for patients with severe major depression, only 50-65% of them attain full remission following ECT. After successful ECT, approximately 50% of those in remission will relapse within a year. The aim of this thesis was to contribute to improving these results. We determined predictors of efficacy of ECT and predictors of relapse after successful ECT to better tailor treatment to the patient and thereby improve the remission and relapse rates. Furthermore, we investigated whether the addition of nortriptyline to a course of ECT enhances its efficacy and prevents relapse after successful ECT.
- More information
The public defence will begin exactly at 13.00 hrs. The doors will be closed once the public defence starts, latecomers can access the hall via the fourth floor. Due to the solemn nature of the ceremony, we recommend that you do not take children under the age of 6 to the first part of the ceremony.
A live stream link has been provided to the candidate.