PhD defence P. (Paola) Pisterzi

The Making of the Hematopoietic Niche

P. Pisterzi will defend her PhD dissertation on Wednesday 13 September, entitled: ’The Making of the Hematopoietic Niche‘.

Promotor
Prof.dr. H.G.P. Raaijmakers
Co-promotor
Dr. T. Cupedo
Date
Wednesday 13 Sep 2023, 13:00 - 14:30
Type
PhD defence
Space
Professor Andries Querido room
Building
Education Center
Location
Erasmus MC
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Below is a brief summary of the dissertation:

The bone marrow niche provides instructional signals to ensure the maintenance and function of haematopoietic stem cells (HSC) and orchestrates the development, maintenance and regeneration of bone marrow. HSC niches have already been the focus of numerous studies, but a better understanding of populations and molecular pathways that drive bone marrow (re)generation is still still required. Unravelling the key players involved in these processes
involved is particularly relevant in the context of therapy-induced bone marrow injury and may help discover treatments that can promote bone marrow repair can promote. In this thesis, we studied the microenvironment of the bone marrow during development and in the context of recovery after chemotherapeutic injury, to shed more light on populations and pathways that play a key role in the above processes.

More information

The public defence will begin exactly at 13.00 hrs. The doors will be closed once the public defence starts, latecomers can access the hall via the fourth floor. Due to the solemn nature of the ceremony, we recommend that you do not take children under the age of 6 to the first part of the ceremony.

A live stream link has been provided to the candidate.

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