PhD defence Y. (Ylenia) Ingrasciotta

Insight into Real-world use and Benefit-risk Profile of Biologics and Frequently Prescribed Drugs in Aging Populations
Promotor

Prof.dr. F.U.S. Mattace Raso

Promotor

Prof.dr. G. Trifiro'

Date
Thursday 1 Sep 2022, 10:30 - 12:00
Type
PhD defence
Space
Senate Hall
Building
Erasmus Building
Location
Campus Woudestein
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On Thursday, 1 September 2022, Y. (Ylenia) Ingrasciotta will defend her PhD dissertation, entitled: ‘Insight into Real-world use and Benefit-risk Profile of Biologics and Frequently Prescribed Drugs in Aging Populations’.

Dissertation in short:

Elderly patients are often not included in randomized clinical trials (RCTs) evaluating efficacy and safety of new drugs. Such exclusions may impair the generalizability of RCT results in real-world settings. Therefore, drugs prescription, especially biologic drugs, to elderly is challenging. The increasing use of biologics in clinical practice gave rise to safety concerns, such as the risk of hypersensitivity reactions, immunogenicity, infections and cancer. The pressing need for thorough post-marketing monitoring of these drugs became clear. The availability and secondary use of claims databases with electronic health records of millions of persons offer the opportunity to get better insights into real-world drug use and the risks and benefits of those medications in community dwelling elderly persons.

More information

The public defence will begin exactly at 10.30 hrs. The doors will be closed once the public defence starts, latecomers may be able to watch on the screen outside. There is no possibility of entrance during the first part of the ceremony. Due to the solemn nature of the ceremony, we recommend that you do not take children under the age of 6 to the first part of the ceremony.

A live stream link has been provided to the candidate.

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