dr. H El Marroun
Assistant Professor Erasmus School of Social and Behavioural Sciences Department of Psychology, Education & Child Studies/ Clinical Psychology
- Location
- Burg. Oudlaan 50, Rotterdam
- Room
- W T13-39
- Telephone
- +31104082410
- elmarroun@essb.eur.nl
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Profile
My research area focuses on the short and long term consequences of maternal and fetal health on brain developmental features, including behaviour and cognition, as well as brain morphology and connectivity. From a developmental origins of health and disease (DoHaD) perspective, non-optimal health during the specific critical period in early life (e.g. due to prenatal exposure to substance use, medication, stress and disease) may have potential long term consequences on health and (brain) development later in life.
My research area focuses on the short and long term consequences of maternal and fetal health on brain developmental features, including behaviour and cognition, as well as brain morphology and connectivity. From a developmental origins of health and disease (DoHaD) perspective, non-optimal health during the specific critical period in early life (e.g. due to prenatal exposure to substance use, medication, stress and disease) may have potential long term consequences on health and (brain) development later in life.
- K. Bolhuis, E. Viding, R.L. Muetzel, H. El Marroun, D. Kocevska, T.J.H. White, H.W. Tiemeier & C.A.M. Cecil (2019). Neural Profile of Callous Traits in Children: A Population-Based Neuroimaging Study. Biological Psychiatry, 85 (5), 399-407. doi: 10.1016/j.biopsych.2018.10.015
- M.H.G. Dremmen, R.H. Bouhuis, L.M.E. Blanken, R.L. Muetzel, M.W. Vernooij, H. El Marroun, V.W.V.K. Jaddoe, F.C. Verhulst, H.W. Tiemeier & T.J.H. White (2019). Cavum Septum Pellucidum in the General Pediatric Population and Its Relation to Surrounding Brain Structure Volumes, Cognitive Function, and Emotional or Behavioral Problems. American Journal of Neuroradiology, 40 (2), 340-346. doi: 10.3174/ajnr.A5939
- N.M. Molenaar, H.W. Tiemeier, E.F.C. van Rossum, M.H.J. Hillegers, C. Bockting, W.J.G. Hoogendijk, E.L.T. van den Akker, M.P. Lambregtse-van den Berg & H. El Marroun (2019). Prenatal maternal psychopathology and stress and offspring HPA axis function at 6 years. Psychoneuroendocrinology, 99, 120-127. doi: 10.1016/j.psyneuen.2018.09.003
- H. El Marroun, K. Bolhuis, I.H.A. Franken, V.W.V.K. Jaddoe, M.H.J. Hillegers, B. Lahey & H. Tiemeier (2019). Preconception and prenatal cannabis use and the risk of behavioural and emotional problems in the offspring; a multi-informant prospective longitudinal study. International Journal of Epidemiology, 48 (1), 287-296. doi: 10.1093/ije/dyy186
- H. El Marroun, R. Zou, R.L. Muetzel, V.W.V.K. Jaddoe, F.C. Verhulst, T.J.H. White & H.W. Tiemeier (2018). Prenatal exposure to maternal and paternal depressive symptoms and white matter microstructure in children. Depression and Anxiety, 35 (4), 321-329. doi: 10.1002/da.22722
- M. Guxens, M.J. Lubczynska, R.L. Muetzel, A. Dalmau-Bueno, V.W.V.K. Jaddoe, G. Hoek, A. van der Lugt, F.C. Verhulst, T.J.H. White, B. Brunekreef, H.W. Tiemeier & H. El Marroun (2018). Air Pollution Exposure During Fetal Life, Brain Morphology, and Cognitive Function in School-Age Children. Biological Psychiatry, 84 (4), 295-303. doi: 10.1016/j.biopsych.2018.01.016
- D. Vojinovic, H. Adams, X.Q. Jian, Q. Yang, A. Smith, J. Bis, A. Teumer, M. Scholz, N. Armstrong, E. Hofer, Y. Saba, M. Luciano, M. Bernard, S. Trompet, J. Yang, N. Gillespie, S.J. van der Lee, A. Neumann, S. Ahmad, O. Andreassen, D. Ames, N. Amin, K. Arfanakis, M. Bastin, D. Becker, A. Beiser, F. Beyer, H. Brodaty, R. Bryan, R. Bulow, A. Dale, P. De Jager, I. Deary, C. DeCarli, D. Fleischman, R. Gottesman, J. van der Grond, V. Gudnason, T.B. Harris, G. Homuth, D. Knopman, J. Kwok, C. Lewis, S. Li, M. Loeffler, O. Lopez, P. Maillard, H. El Marroun, K. Mather, T. Mosley, R.L. Muetzel, M. Nauck, P. Nyquist, M.S. Panizzon, Z. Pausova, B.M. Psaty, K. Rice, J. Rotter, N. Royle, C. Satizabal, R. Schmidt, P.R. Schofield, P. Schreiner, S. Sidney, D. Stott, A. Thalamuthu, A.G. Uitterlinden, M. Hernandez, M.W. Vernooij, W. Wen, T.J.H. White, A.V. Witte, K. Wittfeld, M. Wright, L. Yanek, H.W. Tiemeier, W.S. Kremen, D. Bennett, J.W. Jukema, T. Paus, J. Wardlaw, H. Schmidt, P. Sachdev, A. Villringer, H. Grabe, W.T. Longstreth, C.M. van Duijn, L. Launer, S. Seshadri, M.A. Ikram & M. Fornage (2018). Genome-wide association study of 23,500 individuals identifies 7 loci associated with brain ventricular volume. Nature Communications, 9 (1):3945. doi: 10.1038/s41467-018-06234-w [go to publisher's site]
- H. El Marroun, Q.L. Brown, I.O. Lund, V.H. Coleman-Cowger, A.M. Loree, D. Chawla & Y. Washio (2018). An epidemiological, developmental and clinical overview of cannabis use during pregnancy. Preventive Medicine, 116, 1-5. doi: 10.1016/j.ypmed.2018.08.036
- M.G. Meentken, I.M. van Beynum, E.W.C. Aendekerk, J.S. Legerstee, H. El Marroun, J. van der Ende, R.J.L. Lindauer, M.H.J. Hillegers, H.A. Moll, W.A. Helbing & E.M.W.J. Utens (2018). Eye movement desensitization and reprocessing (EMDR) in children and adolescents with subthreshold PTSD after medically related trauma: design of a randomized controlled trial. European Journal of Psychotraumatology, 9 (1):1536287. doi: 10.1080/20008198.2018.1536287 [go to publisher's site]
- T.J.H. White, P.R. Jansen, R.L. Muetzel, G. Sudre, H. El Marroun, H.W. Tiemeier, A.Q. Qiu, P. Shaw, A. Michael & F.C. Verhulst (2018). Automated quality assessment of structural magnetic resonance images in children: Comparison with visual inspection and surface-based reconstruction. Human Brain Mapping, 39 (3), 1218-1231. doi: 10.1002/hbm.23911
- T.J.H. White, R.L. Muetzel, H. El Marroun, L.M.E. Blanken, P.R. Jansen, K. Bolhuis, D. Kocevska, S.E. Mous, R.H. Mulder, V.W.V.K. Jaddoe, A. van der Lugt, F.C. Verhulst & H.W. Tiemeier (2018). Paediatric population neuroimaging and the Generation R Study: the second wave. European Journal of Epidemiology, 33 (1), 99-125. doi: 10.1007/s10654-017-0319-y
- N. van der Knaap, F. Klumpers, H. El Marroun, S.E. Mous, D. Schubert, V.W.V.K. Jaddoe, A. Hofman, J. Homberg, H.W. Tiemeier, T.J.H. White & G. Fernandez (2018). Maternal depressive symptoms during pregnancy are associated with amygdala hyperresponsivity in children. European Child & Adolescent Psychiatry, 27 (1), 57-64. doi: 10.1007/s00787-017-1015-x
- K. Bolhuis, S.A. Kushner, S. Yalniz, M.H.J. Hillegers, V.W.V.K. Jaddoe, H.W. Tiemeier & H. El Marroun (2018). Maternal and paternal cannabis use during pregnancy and the risk of psychotic-like experiences in the offspring. Schizophrenia Research, 202, 322-327. doi: 10.1016/j.schres.2018.06.067
- R.L. Muetzel, L.M.E. Blanken, J. Ende, H. El Marroun, P. Shaw, G. Sudre, A. van der Lugt, V.W.V.K. Jaddoe, F.C. Verhulst, H. Tiemeier & T.J.H. White (2018). Tracking Brain Development and Dimensional Psychiatric Symptoms in Children: A Longitudinal Population-Based Neuroimaging Study. American Journal of Psychiatry, 175 (1), 54-62. doi: 10.1176/appi.ajp.2017.16070813
- J. Verdejo-Roman, L. Bjornholm, R.L. Muetzel, F. Torres-Espinola, J. Lieslehto, V.W.V.K. Jaddoe, D. Campos, J. Veijola, T. White, A. Catena, J. Nikkinen, M. Jarvelin, H. Tiemeier, C. Campoy, S. Sebert & H. El Marroun (2018). Maternal prepregnancy body mass index and offspring white matter microstructure: results from three birth cohorts. International Journal of Obesity, 202, 322-327. doi: 10.1038/s41366-018-0268-x [go to publisher's site]
- F.O.L. Vehmeijer, M. Guxens, L. Duijts & H. El Marroun (2018). Maternal psychological distress during pregnancy and childhood health outcomes: a narrative review. Journal of Developmental Origins of Health and Disease, 1-12. doi: 10.1017/S2040174418000557
- J. Steenweg-de Graaff, S.J. Roza, A.N. Walstra, H. El Marroun, E.A.P. Steegers, V.W.V. Jaddoe, A. Hofman, F.C. Verhulst, H. Tiemeier & T. White (2017). Associations of maternal folic acid supplementation and folate concentrations during pregnancy with foetal and child head growth: the Generation R Study. European Journal of Nutrition, 56 (1), 65-75. doi: 10.1007/s00394-015-1058-z
- K. Cheung, H. El Marroun, M.E. Elfrink, V.W.V. Jaddoe, L.E. Visser & B.H.C. Stricker (2017). The concordance between self-reported medication use and pharmacy records in pregnant women. Pharmacoepidemiology and Drug Safety, 26 (9), 1119-1125. doi: 10.1002/pds.4264
- H. El Marroun, T. White, G. Fernandez, V.W.V. Jaddoe, F.C. Verhulst & B.H.C. Stricker (2017). Prenatal exposure to selective serotonin reuptake inhibitors and non-verbal cognitive functioning in childhood. Journal of Psychopharmacology, 31 (3), 346-355. doi: 10.1177/0269881116665335
- S.E. Mous, T. White, R.L. Muetzel, H. El Marroun, J. Rijlaarsdam, T.J. Polderman, V.W.V. Jaddoe, F.C. Verhulst, D. Posthuma & H. Tiemeier (2017). Cortical morphology as a shared neurobiological substrate of attention-deficit/hyperactivity symptoms and executive functioning: a population-based pediatric neuroimaging study. Journal of Psychiatry & Neuroscience, 42 (2), 103-112. doi: 10.1503/jpn.150371
- M.R. Radojcic, H. El Marroun, B. Miljkovic, B.H.C. Stricker, V.W.V. Jaddoe, F.C. Verhulst & H. Tiemeier (2017). Prenatal exposure to anxiolytic and hypnotic medication in relation to behavioral problems in childhood: A population-based cohort study. Neurptoxicology And Teratology, 61, 58-65. doi: 10.1016/j.ntt.2017.02.005
- R Chen, R.L. Muetzel, H. El Marroun, G. Noppe, E.F. van Rossum, V.W.V. Jaddoe, F.C. Verhulst, T. White, F. Fang & H. Tiemeier (2016). No association between hair cortisol or cortisone and brain morphology in children. Psychoneuroendocrinology, 74, 101-110. doi: 10.1016/j.psyneuen.2016.08.023
- C.L. Ars, I.M. Nijs, H. El Marroun, R.L. Muetzel, M. Schmidt, J. Steenweg-de Graaff, A. Van der Lugt, V.W.V. Jaddoe, A. Hofman, E.A.P. Steegers, F.C. Verhulst, H. Tiemeier & T. White (2016). Prenatal folate, homocysteine and vitamin B12 levels and child brain volumes, cognitive development and psychological functioning: the Generation R Study. British Journal of Nutrition, 22, 1-9. doi: 10.1017/S0007114515002081
- H. El Marroun, H. Tiemeier, I.H.A. Franken, V.W.V.K. Jaddoe, A. van der Lugt, F.C. Verhulst, B. Lahey & T. White (2016). Prenatal Cannabis and Tobacco Exposure in Relation to Brain Morphology: A Prospective Neuroimaging Study in Young Children. Biological Psychiatry, 79 (12), 971-979. doi: 10.1016/j.biopsych.2015.08.024
- G. Van den Brink, L. Stapersma, H. El Marroun, J. Henrichs, E.M. Szigethy, E.M. Utens & J.C. Escher (2016). Effectiveness of disease-specific cognitive-behavioural therapy on depression, anxiety, quality of life and the clinical course of disease in adolescents with inflammatory bowel disease: study protocol of a multicentre randomised controlled trial (HAPPY-IBD). BMJ Open Gastroenterology, 3 (1). doi: 10.1136/bmjgast-2015-000071
- H. El Marroun, H. Tiemeier, R.L. Muetzel, S. Thijssen, N.J. van der Knaap, V.W.V. Jaddoe, G. Fernandez, F.C. Verhulst & T. White (2016). Prenatal exposure to maternal and paternal depressive symptoms and brain morphology: a population-based prospective neuroimaging study in young children. Depression and Anxiety, 33 (7), 658-666. doi: 10.1002/da.22524
- L.M.E. Blanken, S.E. Mous, A. Ghassabian, R.L. Muetzel, N.K. Schoemaker, H. El Marroun, A. Van der Lugt, V.W.V. Jaddoe, A. Hofman, F.C. Verhulst, H. Tiemeier & T. White (2015). Cortical morphology in 6- to 10-year old children with autistic traits: a population-based neuroimaging study. American Journal of Psychiatry, 172 (5), 479-486. doi: 10.1176/appi.ajp.2014.14040482
- G.E. van den Bosch, T. White, H. El Marroun, S.H. Simons, A. Van der Lugt, J.N. van der Geest, D. Tibboel & M. Van Dijk (2015). Prematurity, Opioid Exposure and Neonatal Pain: Do They Affect the Developing Brain? Neonatology, 108 (1), 8-15. doi: 10.1159/000376566
- S. Thijssen, A. Wildeboer, R.L. Muetzel, M. Bakermans-Kranenburg, H. El Marroun, A. Hofman, V.W.V. Jaddoe, A. van der Lugt, F.C. Verhulst, H.W. Tiemeier, M.H. van IJzendoorn & T. White (2015). Cortical thickness and prosocial behavior in school-age children: A population-based MRI study. Social Neuroscience, 10 (6), 571-582. doi: 10.1080/17470919.2015.1014063
- S. Thijssen, A.P. Ringoot, A. Wildeboer, M. Bakermans-Kranenburg, H. El Marroun, A. Hofman, V.W.V. Jaddoe, F.C. Verhulst, H.W. Tiemeier, M.H. van IJzendoorn & T. White (2015). Brain morphology of childhood aggressive behavior: A multi-informant study in school-age children. Cognitive, Affective and Behavioral Neuroscience, 15 (3), 564-577. doi: 10.3758/s13415-015-0344-9
- H. El Marroun, T. White, F.C. Verhulst & H. Tiemeier (2014). Maternal use of antidepressant or anxiolytic medication during pregnancy and childhood neurodevelopmental outcomes: a systematic review. European Child & Adolescent Psychiatry, 23 (10), 973-992. doi: 10.1007/s00787-014-0558-3
- H. El Marroun, M.N. Schmidt, I.H.A. Franken, V.W.V. Jaddoe, A. Hofman, A. Van der Lugt, F.C. Verhulst, H. Tiemeier & T. White (2014). Prenatal tobacco exposure and brain morphology: a prospective study in young children. Neuropsychopharmacology, 39 (4), 792-800. doi: 10.1038/npp.2013.273
- A. Ghassabian, H. El Marroun, R.P. Peeters, V.W.V. Jaddoe, A. Hofman, F.C. Verhulst, H. Tiemeier & T. White (2014). Downstream effects of maternal hypothyroxinemia in early pregnancy: nonverbal IQ and brain morphology in school-age children. Journal of Clinical Endocrinology and Metabolism, 99 (7), 2383-2390. doi: 10.1210/jc.2013-4281
- N.J. van der Knaap, H. El Marroun, F. Klumpers, S.E. Mous, V.W.V. Jaddoe, A. Hofman, J. Homberg, T. White, H. Tiemeier & G. Fernandez (2014). Beyond classical inheritance: the influence of maternal genotype upon child's brain morphology and behavior. Journal of Neuroscience, 34 (29), 9516-9521. doi: 10.1523/JNEUROSCI.0505-14.2014.
- H. El Marroun, T. White, N.J. van der Knaap, J. Homberg, G. Fernandez, N.K. Schoemaker, V.W.V. Jaddoe, A. Hofman, F.C. Verhulst, J.J. Hudziak, B.H.C. Stricker & H. Tiemeier (2014). Prenatal exposure to selective serotonin reuptake inhibitors and social responsiveness symptoms of autism: population-based study of young children. British Journal of Psychiatry, 205 (2), 95-102. doi: 10.1192/bjp.bp.113.127746
- G.E. van den Bosch, H. El Marroun, M.N. Schmidt, D. Tibboel, D. Manoach & V. Calhoun (2014). Brain connectivity during verbal working memory in children and adolescents. Human Brain Mapping, 35 (2), 698-711. doi: 10.1002/hbm.22193
- M.E. Elfrink, H.A. Moll, J. Kiefte-de Jong, H. El Marroun, V.W.V. Jaddoe, A. Hofman, B.H. Stricker, J.M. ten Cate & J.S. Veerkamp (2013). Is maternal use of medicines during pregnancy associated with deciduous molar hypomineralisation in the offspring? A prospective, population-based study. Drug Safety, 36 (8), 627-633. doi: 10.1007/s40264-013-0078-y
- N.H. van Mil, R.P.M. Steegers-Theunissen, J.J. Schokking, H. El Marroun, A. Ghassabian, A. Hofman, V.W.V. Jaddoe, T.J. Visser, F.C. Verhulst, Y. de Rijke, E.A.P. Steegers & H. Tiemeier (2012). Maternal hypothyroxinemia during pregnancy and growth of the fetal and infant head. Reproductive Sciences, 19 (12), 1315-1322. doi: 10.1177/1933719112450338
- H. El Marroun, V.W.V. Jaddoe, J.J. Hudziak, S.J. Roza, E.A.P. Steegers, A. Hofman, F.C. Verhulst, T. White, B.H. Stricker & H. Tiemeier (2012). Maternal use of selective serotonin reuptake inhibitors, fetal growth, and risk of adverse birth outcomes. Archives of General Psychiatry, 69 (7), 706-714. doi: 10.1001/archgenpsychiatry.2011.2333
- H. El Marroun, M. Zeegers, E.A.P. Steegers, J. van der Ende, J. Schenk, A. Hofman, V.W.V. Jaddoe, F.C. Verhulst & H. Tiemeier (2012). Post-term birth and the risk of behavioural and emotional problems in early childhood. International Journal of Epidemiology, 41 (3), 773-781. doi: 10.1093/ije/dys043
- H. El Marroun, H. Tiemeier, V.W.V. Jaddoe, A. Hofman, F.C. Verhulst, W. Van den Brink & A.C. Huizink (2011). Agreement between maternal cannabis use during pregnancy according to self-report and urinalysis in a population-based cohort: the Generation R Study. European Addiction Research, 17 (1), 37-43. doi: 10.1159/000320550
- J.J. Geelhoed, H. El Marroun, B.O. Verburg, L. van Osch-Gevers, A. Hofman, A.C. Huizink, H.A. Moll, F.C. Verhulst, W.A. Helbing, E.A.P. Steegers & V.W.V. Jaddoe (2011). Maternal smoking during pregnancy, fetal arterial resistance adaptations and cardiovascular function in childhood. Bjog-An International Journal of Obstetrics and Gynaecology, 118 (6), 755-762. doi: 10.1111/j.1471-0528.2011.02900.x
- H. El Marroun, J.J. Hudziak, H. Tiemeier, H. Creemers, E.A.P. Steegers, V.W.V. Jaddoe, A. Hofman, F.C. Verhulst, W. Van den Brink & A.C. Huizink (2011). Intrauterine cannabis exposure leads to more aggressive behavior and attention problems in 18-month-old girls. Drug & Alcohol Dependence, 118 (2-3), 470-474. doi: 10.1016/j.drugalcdep.2011.03.004
- H. El Marroun, H. Tiemeier, E.A.P. Steegers, J.W. Roos-Hesselink, V.W.V. Jaddoe, A. Hofman, F.C. Verhulst, W. Van den Brink & A.C. Huizink (2010). A prospective study on intrauterine cannabis exposure and fetal blood flow. Early Human Development, 86 (4), 231-236. doi: 10.1016/j.earlhumdev.2010.03.006
- H. El Marroun, H. Tiemeier, E.A.P. Steegers, V.W.V. Jaddoe, A. Hofman, F.C. Verhulst, W. Van den Brink & A.C. Huizink (2009). Intrauterine cannabis exposure affects fetal growth trajectories: the Generation R Study. Journal of the American Academy of Child and Adolescent Psychiatry, 48 (12), 1173-1181. doi: 10.1097/CHI.0b013e3181bfa8ee
- M.J. Lubczyńska & H. El Marroun (2018). Luchtverontreiniging doet schade aan kinderbrein : onderzoek naar gevolgen blootstelling fijnstof tijdens zwangerschap = Research into the Effects of Exposure to Particulate Matter During Pregnancy: Air Pollution Damages Children's Brain. Pharmaceutisch Weekblad, 153 (20), 24-25.
Kinder- en jeugdpsychiatrie
- Title
- Kinder- en jeugdpsychiatrie
- Year
- 2018
- Year level
- (Bachelor 3)
Assistant Professor
- University
- Erasmus University Rotterdam
- School
- Erasmus School of Social and Behavioural Sciences
- Department
- Department of Psychology, Education & Child Studies/ Clinical Psychology
- Country
- The Netherlands
- Telephone
- +31104082410
Academic Researcher
- University
- Erasmus University Rotterdam
- School
- Erasmus MC
- Department
- Generation R
- Country
- The Netherlands
Assistant Professor
- University
- Erasmus University Rotterdam
- School
- Erasmus MC
- Department
- pediatric psychiatry
- Country
- The Netherlands
Assistant Professor
- University
- Erasmus MC
- Department
- the Netherlands
- Country
- the Netherlands
- Telephone
- 010-7036086